Technical Applications Scientist
Role details
Job location
Tech stack
Job description
You will play a hands-on role in the development, optimisation, and validation of the Pictura Bio assay. Working closely with assay development, imaging, and data science teams, you will support the transition of a research-stage assay into a robust, reproducible diagnostic workflow.
This role is fully on-site and laboratory-based, and is suited to a scientist with strong experimental skills, experience in fluorescence microscopy, and an understanding of working within a quality-managed environment. You will be expected to generate high-quality experimental data, document work rigorously, and contribute to assay robustness, reproducibility, and performance verification.
Major Accountabilities
· Design, execute, and document laboratory experiments supporting assay development
· Optimise fluorescence labelling protocols for viruses, bacteria, and other pathogens
· Perform fluorescence microscopy imaging using standardised protocols
· Support development and refinement of imaging workflows (sample prep, imaging parameters)
· Analyse experimental data and contribute to interpretation of assay performance
· Verify and validate assay performance (e.g. repeatability, sensitivity, specificity, robustness)
· Maintain accurate, detailed laboratory records in line with quality requirements
· Contribute to SOPs, protocols, and technical documentation
· Work in accordance with company quality systems, policies, and procedures
· Collaborate closely with assay, imaging, and software teams to support end-to-end assay development
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Requirements
· BSc or MSc in a relevant discipline (e.g. Biophysics, Biomedical Sciences, Microbiology, Molecular Biology, Bioengineering)
· PhD desirable but not essential
Experience
· Hands-on laboratory experience in assay development or bioanalytical testing
· Practical experience with fluorescence microscopy (widefield, epifluorescence, TIRF, or confocal)
· Experience working under a Quality Management System (e.g. ISO 13485, ISO 15189, GLP, GxP, or similar)
· Experience in an industrial, translational, or regulated laboratory environment is highly desirable
Skills
· Strong experimental and practical laboratory skills
· Good understanding of assay development principles and experimental controls
· Familiarity with fluorescence labelling and sample preparation
· Ability to follow and improve SOPs and experimental protocols
· Strong attention to detail and excellent record-keeping
· Comfortable analysing data and reporting results clearly
· Familiarity with image analysis software is an advantage
· Basic Python or data analysis skills are beneficial but not essential
Personal Attributes
· Methodical, careful, and data/quality-driven
· Comfortable working in a fast-moving, early-stage company
· Willing to challenge results constructively and troubleshoot experiments
· Collaborative and communicative Similar jobs